Most people can imagine how does Viagra work, since it is widely known for more than twenty years. In addition, men learn more on how does Viagra work because impotence is spreading, so even younger patients complain of erectile dysfunction. Fortunately, anyone can get rid of these difficulties with the help of this wonderful medication.
First, let us understand how does Viagra work in most simple words. A man takes one pills at a dose of 25 mg to 100 mg about thirty minutes before making love. Then, but only in case of natural arousal sue to sexual stimulation, a hard and prolonged erection appears. Mind that Viagra works best if you take it on an empty stomach, without alcohol or grapefruit juice, and do not break it or chew. In fact, better first read the instructions, and follow them strictly.
Too heavy or fatty meals, grapefruit in any form, and alcoholic beverages could negatively affect the action of Viagra and cause unpleasant side effects. In case you have done everything right, as soon as in twenty minutes you will have a strongest boner ever. Erection could last for four hours, and will disappear after you have an orgasm. Still, if you wish, you can make love several times.
Viagra works in such a way due to its main active ingredient Sildenafil, which is a selective PDE-5 enzyme inhibitor. It blocks the negative effect of PDE-5 on the cavernous tissue of the penis, relaxes smooth muscles, and increases blood flow in the genital area. Furthermore, Viagra enhances pleasant sensations during sex, so many men use the pills as a recreational drug.
In other words, a scientific answer to the question, how does Viagra work, lies in the properties of its active substance. Sildenafil, as an inhibitor of the enzyme called cGMP-specific phosphodiesterase type 5 (PDE5), triggers several processes in the male body at once. While PDE5 suppresses erection, Viagra blocks its bad action. Due to this, any man can quickly and without effort get an erection, and a hard-on will last really long. Usually, the blue pill lasts for four to six hours, but some patients feel the effect much longer. How does Viagra work also depends on genetic factors. Sildenafil is effective in 50% of carriers of the GNB3 825C-allele and in more than 90% of the TT genotype carriers.
How does Viagra work in people who have severe impotence? It could still help if you follow the recommendations, take the drug properly, and pick up the right dosage. On average, MD recommend to start with 50 mg Viagra pills. If you notice side effects, you might decrease the dose. On the opposite, if it does not seem enough, you can increase the dose. Mind that, according to studies, most men have to take Viagra 6-8 times to notice positive changes.